Dr. Sara Tancredi

Dr. Sara Tancredi is a fictional character from the American television series, Prison Break. She is played by Sarah Wayne Callies. As one of the main characters in the series, the character has appeared in almost every episode. Her main role in the first season of the series is as a prison doctor and the love interest of the protagonist, Michael Scofield (played by Wentworth Miller). As the season progresses, Sara's role expands with her increased involvement in the main plot. In the second season, the evolution of the character further increases her role as one of the show's main characters.

Raised in Chicago, Sara Tancredi's ambitions to be a doctor began when she was very young. While at Northwestern University, she was introduced to the works of Mahatma Gandhi and decided to become a humanitarian, which later influenced her decision to work at Fox River State Penitentiary. Another factor which contributed to her occupational choice was her past morphine addiction, culminating in being unable to help a boy after he was run over due to being high, which was revealed in a flashback episode of the first season, "Brother's Keeper". At 29 years old, Dr. Sara Tancredi was one of the few doctors working at Fox River. Her chosen occupation became a constant source of stress for her father. Sara is the only child of the Governor of Illinois, Frank Tancredi (played by John Heard). Due to her father's hectic political career and vastly differing beliefs, she did not have a close relationship with him. In episode "Buried", it was revealed that her mother has already died.

As one of the few doctors on staff, Sara is responsible for everything from administering physicals to performing emergency surgery. Though Sara doesn’t think twice about the risks she puts herself in every day, it is a constant source of stress for her father, Illinois Governor “Frontier Justice” Frank Tancredi. That, along with their vastly different political beliefs, has cooled their relationship significantly in recent years.

But despite her history of drugs, no one would have predicted however, that Sara would have ever engaged in criminal activity. Immediately following the Fox River eight’s escapes, authorities discovered that the infirmary door was left unlocked, thereby allowing the inmates to access an easy escape route from the prison. After questioning several Fox River employees in the medical wing, Sara became a prime suspect in aiding and abetting the escape; it appeared it was she –who left the door open.

When Chicago PD arrived at her apartment to question her, they found her in a coma, having overdosed from morphine. However, Sara recuperated fairly quickly and was taken into custody for questioning. Governor Tancredi posted her bail, but was later found dead in his residence from apparent suicide. Sara has been at large since leaving the state.